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Discovery of best stabilizing agents for lyophilized enzyme and antibody reagents in long-term room temperature storage conditions

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Ottawa-based Evik Diagnostics manufactures lyophilized/freeze-dried reagents for a large US environmental testing company. They are now ramping up pilot manufacturing to support entry to other export markets, including Canada. Through this project, Evik will collaborate with Dr. Frank Merante and student research assistants from Seneca’s School of Biological Sciences and Applied Chemistry (BSAC) to develop of a point-of-use immunoassay employing reagents with an extended shelf life at room temperature that will complement the existing Evik product pipeline. The research focus will be on investigating novel ways to create prolonged stability through the introduction of excipients to the base reagents, and will concurrently provide the opportunity to enhance enzymatic activity and associated assay performance.

Funder: Natural Sciences and Engineering Research Council (NSERC).