BIO198 - Advanced Biology

Outline info
Last revision date 2018-07-20 12:28:54.022
Last review date 2018-07-20 12:29:05.139

Subject Title
Advanced Biology

Subject Description
In this advanced course, students engage in a theoretical and practical investigation of the concepts and processes of biological systems. Areas of study include cellular metabolism, gene expression and regulation, genetic inheritance, evolution, and a detailed exploration of the anatomy and function of different organ systems in the maintenance of homeostasis. This course prepares students for post-secondary level studies of the life sciences and its related fields.
This course contains equivalent content to SBI4U, but it is not a ministry approved credit.

Credit Status

Learning Outcomes
Upon successful completion of this subject the student will be able to:

1.      Explain the relationships between identified human body systems, homeostasis, and health.
2.      Explain the thermodynamics of cellular metabolism.
3.      Explain how cell organelles, enzymes and other biological molecules are involved in aerobic and anaerobic cellular respiration.
4.      Explain the concepts of gene expression and the roles of DNA, RNA, and chromosomes in cellular metabolism, growth, and division.
5.      Explain the genetic and epigenetic aspects of gene regulation.
6.      Analyze the personal, ethical, sociocultural, economic and environmental impacts of changes being brought about by biological research.
7.      Explain lab safety protocols to ensure a safe environment for self and others.

Essential Employability Skills
Communicate clearly, concisely and correctly in the written, spoken and visual form that fulfils the purpose and meets the needs of the audience.

Execute mathematical operations accurately.

Locate, select, organize, and document information using appropriate technology and information systems.

Analyze, evaluate, and apply relevant information from a variety of sources.

Show respect for diverse opinions, values, belief systems, and contributions of others.

Interact with others in groups or teams in ways that contribute to effective working relationships and the achievement of goals.

Manage the use of time and other resources to complete projects.

Take responsibility for one's own actions, decisions, and consequences.

Cheating and Plagiarism
Each student should be aware of the College's policy regarding Cheating and Plagiarism. Seneca's Academic Policy will be strictly enforced.

To support academic honesty at Seneca College, all work submitted by students may be reviewed for authenticity and originality, utilizing software tools and third party services. Please visit the Academic Honesty site on for further information regarding cheating and plagiarism policies and procedures.

All students and employees have the right to study and work in an environment that is free from discrimination and/or harassment. Language or activities that defeat this objective violate the College Policy on Discrimination/Harassment and shall not be tolerated. Information and assistance are available from the Student Conduct Office at

Accommodation for Students with Disabilities
The College will provide reasonable accommodation to students with disabilities in order to promote academic success. If you require accommodation, contact the Counselling and Disabilities Services Office at ext. 22900 to initiate the process for documenting, assessing and implementing your individual accommodation needs.

BIO091 (Grade B or higher) or Grade 11 C/U Biology

Topic Outline

  1. Digestive System
·         Function and structure of organs and accessory organs
·         Histology of GI tract
·         Digestive processes
·         Main substrates, digestion end-products and absorption
·         Digestive enzymes, hormones and chemicals
  1. Cellular Metabolism
·         Laws of thermodynamics, functional groups of molecules, energy transformation in the cell, cellular respiration, and photosynthesis
·         Comparison of structure between mitochondrion and chloroplast
·         Technological applications of enzyme activity in the food and pharmaceutical industries
·         Operational definitions of electronegativity, isomer, polymer, solubility, substrate, and reaction rate
  1. Skeletal System
·         Microscopic structure of bone and cartilage
·         Functions of surface markings on bones
·         Identify bone markings for each bone covered in the appendicular and axial skeleton
  1. Circulatory System
·         Blood and Hemostasis: diagnostic importance of blood testing; ABO and Rh group problems; some blood disorders - interesting leukemias and hemostatic disorders
·         Factors affecting blood pressure
·         Identify major arteries and veins
  1. Nervous System
·         General functions of lobes of the cerebrum
·         General functions of major junctional regions of the cerebral cortex
·         Main functions of the 12 cranial nerves
·         Structural and functional differences of the sympathetic and parasympathetic divisions of the ANS
  1. Immune System
·         Innate and adaptive responses
·         Lymphatic system
·         Use of vaccines, antibiotics, antiseptics, and other drug therapies to control the pathogenesis
·         Impact of misuse of antibiotics; importance of aseptic techniques as a means of protection from diseases
  1. Pathogens and Disease
·         Terms - microorganism, pathogen, parasite, disease, pathogenesis, and vector
·         Characteristics and reproductive cycles of representative pathogens - lytic and lysogenic cycle, malaria
·         Modes of disease transmission - insect borne, water borne, food borne, and sexually transmitted
  1. Reproductive System
·         Gross anatomy and function
·         Pregnancy and human development
  1. Evolution
  2. Genetic Inheritance
·         Concepts of DNA; importance of mitosis and meiosis
·         Genetic disorders - Down Syndrome, Fragile X Syndrome
·         Mendelin genetics, concepts of dominance, co-dominance, incomplete dominance, recessiveness, and sex linkage
·         Solving basic genetic problems using Punnett square method; cytogenetics and human diagnosis virtual laboratory; human characteristics laboratory
·         Case studies in genetics; genetics counselling, fetal testing and human gene therapy; genetically modified foods; DNA extraction; impact of cloning on the development of scientific knowledge

Mode of Instruction
Students attend classes on campus each week. All instruction is delivered in a face to face environment.
Teaching and Learning Methods:
To ensure that students are engaged as much as possible in the learning process, instructors can use such teaching methods as class and small group discussions, essays and research, individual and group presentations, readings, lectures, workshops, in-class exercises, and/or web-based instruction. The mode of delivery will dictate the most appropriate teaching methods available to an instructor.

Prescribed Texts
Human Biology, Anatomy and Physiology For the Health Sciences
Wendi Roscoe
Nelson College Indigenous
ISBN - 10: 0176507175
ISBN - 13: 9780176507176

Recommended Texts

Reference Material

Required Supplies

Promotion Policy

Grading Policy
A+ 90%  to  100%
A 80%  to  89%
B+ 75%  to  79%
B 70%  to  74%
C+ 65%  to  69%
C 60%  to  64%
D+ 55%  to  59%
D 50%  to  54%
F 0%    to  49% (Not a Pass)
EXC Excellent
SAT Satisfactory
UNSAT Unsatisfactory

For further information, see a copy of the Academic Policy, available online ( or at Seneca's Registrar's Offices.

Modes of Evaluation
To be successful in this course, you must complete all course work as specified and achieve an overall grade of 50% or higher. For further information on evaluation and academic standing, see a copy of the Academic Policy available at Seneca registration offices.

Please note:  to satisfy the Pre-Health graduation requirements, student's must obtain a minimum grade of 60% if wishing to pursue a BSCN or 65% if wishing to pursue the RPN program.

Grading scheme:

In-Class Evaluation
5 In-Class Worksheets    25%
1 Assignment   5%
2 Tests  30%
3 Labs  10%
Final Exam 30%
Total 100%

Term Work:  All term work assignments must be completed prior to the time of the examination. Unless students have been granted an extension in advance, late take-home assignments will be penalized one letter grade per day and will not be graded after one week (there is no provision for rewriting late assignments, regardless of the grade).  Students must contact faculty in advance of due date to discuss extensions.
If a student has to miss any in-class quiz/test, he/she must notify the faculty via email or phone messages prior to start time of the quiz/test date.  Valid documentation (such as original stamped doctor's note) must be submitted to the faculty on or before the next scheduled class.  Make-up opportunities may be arranged at the Test Centre.

Student Success:

Please come prepared to participate in class. Make sure you bring your course text to each class, participate in class discussions, hand in any assigned work on time and attend each and every class. Following these suggestions will increase your chances of success

Approved by: Fiona Bain-greenwood