- Ontario Secondary School Diploma (OSSD), or equivalent, or a mature applicant
- English: Grade 12 C or U, or equivalent course
- Mathematics: Grade 12 C or U, or Grade 11 Functions (MCR3U), or equivalent course
- Biology: Grade 11 C or U, or equivalent course
- Chemistry: Grade 12 C or U, or equivalent course
Canadian citizens and permanent residents may satisfy the English and/or mathematics requirements for this program through successful Seneca pre-admission testing.